Brazilian Wasp Venom Kills Cancer Cells, But Not Healthy Cells

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Every day there are more and more evidences that the nature can help with the most of our health problems- scientists are now investigating the Brazilian Wasp as they believe that its venom is effective against cancer cells.

Until now, only the entomologists were interested in wasps because they do not make tasty honey, they do not have attractive look and their sting can be quite painful.

Brazilian Wasp Venom Kills Cancer Cells, But Not Healthy Cells

But now it is believed that wasps have their special life-saving secret- the toxin in their venom attacks only cancerous cells, not the healthy ones.

This toxin is known as MP1 (Polybia-MP1). It affects the arrangement of lipids in the membranes of cancerous cells. Simply said, wasp venom makes holes in the membranes of the diseased cells without affecting the healthy cells.

After the venom makes those holes in the cell membranes, the cell is not able to function and at the end, dies.

As quoted in the study findings:

“The MP1 peptide has been shown to have selective inhibition against numerous cancer lines compared to healthy cells. Such malignant cells are also known to have increased expression of PS and PE lipids on their outer plasma membrane. This study strongly correlates the enhanced tumor inhibitory effects of these peptides with this pathological change in plasma membrane lipid composition, where the upregulation of PS and PE lipids can synergistically enhance the membrane-permeabilizing activity of MP1. This membrane permeabilization is likely to be the primary mechanism of cancer cell death induced by these peptides.”

“This suggests that MP1 might be a candidate therapeutic for development of novel cancer therapies, or at least guide the development of novel lead compounds for treatment of these diseases.”

“The selectivity of the MP1 peptide to disrupt the membranes of cancer cells may act synergistically with these other drugs to significantly enhance the therapeutic potency. Therefore, the therapeutic potential of this and other membrane-active peptides within the field of oncology is worthy of further investigation.”

We are always happy to hear about new research going on in the world finding natural treatments against deadly diseases. The future is bright.

 

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Khawar Abbasi


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